DYNC1I2 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Dynein, cytoplasmic 1, intermediate chain 2

Gene Aliases

IC2, DIC74, DNCI2, NEDMIBA

Gene ID

1781

Swiss Prot

Q13409

Accession Number

NP_001369

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DYNC1I2

Target

DYNC1I2 acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes.

Partner Proteins

DYNLRB1; TUBGCP3; SUMO2; UBC; RNF2; EIF3CL; PRUNE2; DYNC1LI1; EIF3K; SERBP1; HNRNPA0; AKAP12; EIF3G; EIF3B; EIF3A; RPS26; RPS13; RPS5; PSMD8; PSMC5; YBX1; MAP2; DYNC1LI2; DYNC1H1; DDX1; ABCF1; vpr; PEX14; VCP; ECT2; CUL3; Dynll1; Dync1i2; SRRM2; DCTN1; PN

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

VAPKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDH

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

71kDa

Protein Length

638

NCBI Gene Symbol

DYNC1I2

Host or Source

Rabbit

Protein Name

Cytoplasmic dynein 1 intermediate chain 2

Gene Name URL

DYNC1I2

Nucleotide Accession Number

NM_001378

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