PAXIP1 Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

PAX interacting (with transcription-activation domain) protein 1

Gene Aliases

PTIP, TNRC2, CAGF28, CAGF29, PACIP1, PAXIP1L

Gene ID

22976

Swiss Prot

Q6ZW49

Accession Number

EAX04525

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PAXIP1

Target

PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation.

Partner Proteins

MAPRE2; POM121; NXT1; PPARG; XAGE1E; SMAD2; SPATA18; COMTD1; BTBD16; DIS3L; LACTB; HNRNPLL; ZNF251; ZNF622; BTBD6; C7orf50; FAM175A; TMEM120A; FAHD1; TM2D3; ATHL1; CENPU; DYNC2H1; BRCC3; KRI1; ANAPC1; NOM1; POLR1E; NCAPG; AASDHPPT; RBM25; CATSPERG; WDR48

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVP

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol