CBX2 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Chromobox homolog 2

Gene Aliases

M33, CDCA6, SRXY5

Gene ID

84733

Swiss Prot

Q14781

Accession Number

NP_005180

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CBX2

Target

CBX2 Contains 1 A.T hook DNA-binding domain and 1 chromo domain. CBX2 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Partner Proteins

KRTAP10-3; KRTAP10-1; KRTAP10-9; KRTAP10-7; RBMY1F; DHX57; KRTAP2-4; RBMY1A1; RNF2; BMI1; MDFI; SOX2; GTF2I; PHC2; CSNK2B; CSNK2A2; CSNK2A1; CENPE; PARP1; CCDC158; DIS3L2; HIST4H4; CBX2; PARP12; RNF213; ZKSCAN7; DCAF6; KDM3A; MYCBP2; ANKRD26; PSME3; TRANK

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPEL

Applications

WB, IP

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol