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SETMAR Antibody - C-terminal region

Product Specifications

Gene Name

SET domain and mariner transposase fusion gene

Gene Aliases

Mar1, METNASE

Gene ID

6419

Swiss Prot

E7EN68

Accession Number

NP_001230652

Reactivity

Human, Cow

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human SETMAR

Target

This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain.

Partner Proteins

CHEK1; H3F3C; tat; PRPF19; SETMAR; RAD9A; PCNA; TOP2A; XRCC4

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

FLQGKRFHNQQDAENAFQEFVESQSTDFYATGINQLISRWQKCVDCNGSY

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

59kDa

Protein Length

545

NCBI Gene Symbol

SETMAR

Host or Source

Rabbit

Protein Name

Histone-lysine N-methyltransferase Ensembl ENSP00000403145

Gene Name URL

SETMAR

CAS Number

9007-83-4

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