NEDD9 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Neural precursor cell expressed, developmentally down-regulated 9

Gene Aliases

CAS2, CASL, HEF1, CAS-L, CASS2

Gene ID

4739

Swiss Prot

Q14511

Accession Number

NP_006394

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human NEDD9

Target

Variation in NEDD9 is associated wih susceptibility to late-onset Alzheimer and Parkinson diseases. Changes in expression of the scaffold protein HEF1/CAS-L/NEDD9 were found to be a potent prometastatic stimulus in melanoma and other cancers.

Partner Proteins

NFKBIA; NAB2; RFX6; PRR20A; BANP; RBPMS; BCAR3; TRIP6; TRIM27; REL; SMAD1; APP; CRK; UBC; PIK3CA; DIMT1; ELSPBP1; NEDD9; ITCH; CHAT; MICAL1; SH2D3C; SMAD3; BCAR1; PXN; CRKL; ZYX; SMAD2; PTK2B; PTK2; NCK1; ID2; RAPGEF1; PTPN12; CDH1; ABL1; PTPN11; LYN; LCK

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

HPPPQLGQSVGSQNDAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLH

Applications

IHC, WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 79%; Horse: 93%; Human: 100%; Mouse: 92%; Rabbit: 79%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

93kDa

Protein Length

834

NCBI Gene Symbol

NEDD9

Host or Source

Rabbit

Protein Name

Enhancer of filamentation 1

Gene Name URL

NEDD9

Nucleotide Accession Number

NM_006403

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