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PTP4A3 antibody - middle region (ARP51193_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Protein tyrosine phosphatase type IVA, member 3

Gene Aliases

PRL3, PRL-3, PRL-R

Gene ID

11156

Swiss Prot

O75365

Accession Number

NP_116000

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PTP4A3

Target

PTP4A3 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs) . PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contains a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth.The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs) . PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist.

Partner Proteins

ELAVL1; FNTB; FNTA; IPO4; MMS19; NCAPG; SMAP1; SRPRB; XPO5; TTC27; FANCI; ATAD3A; TMEM33; HEATR1; DNAAF5; TNPO2; CNNM3; KIAA1279; RAB3GAP2; NUP188; KIAA0368; XPO7; GCN1L1; SMC2; LRPPRC; UBE4A; AIFM1; USO1; ABCD3; PSMD3; PRPSAP1; POLD1; HNRNPM; MSH2; MCM3

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQR

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

19kDa

Protein Length

173

NCBI Gene Symbol

PTP4A3

Host or Source

Rabbit

Protein Name

Protein tyrosine phosphatase type IVA 3

Gene Name URL

PTP4A3

Nucleotide Accession Number

NM_032611

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