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BRF2 antibody - N-terminal region (ARP50630_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like

Gene Aliases

BRFU, TFIIIB50

Gene ID

55290

Swiss Prot

Q9HAW0

Accession Number

NP_060780

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human BRF2

Target

BRF2 is the general activator of RNA polymerase III transcription. BRF2 is the factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites.This gene encodes one of the multiple subunits of the RNA polymerase III transcription factor complex required for transcription of genes with promoter elements upstream of the initiation site. The product of this gene, a TFIIB-like factor, is directly recruited to the TATA-box of polymerase III small nuclear RNA gene promoters through its interaction with the TATA-binding protein.

Partner Proteins

UBC; SNAPC4; TBP; RBL2; IPO4; RNF219; XPO4; SMAP1; SMPD4; FANCI; ATAD3A; TMEM33; DNAAF5; OTUD4; PTPLAD1; GEMIN4; NOC2L; TNPO3; SF3B1; XPO6; XPO7; COPG1; GCN1L1; NUP93; AIFM1; DPM1; SLC3A2; ABCD3; MYO1B; MARS

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

VTEGVLTTTFSDEGNLREVTYSRSTGENEQVSRSQQRGLRRVRDLCRVLQ

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

46kDa

Protein Length

419

NCBI Gene Symbol

BRF2

Host or Source

Rabbit

Protein Name

Transcription factor IIIB 50 kDa subunit

Gene Name URL

BRF2

Nucleotide Accession Number

NM_018310

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