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APC2 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Adenomatosis polyposis coli 2

Gene Aliases

APCL

Gene ID

10297

Swiss Prot

Q9UJX6

Accession Number

NP_005874

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human APC2

Target

APC2 belongs to the adenomatous polyposis coli (APC) family. It contains 6 ARM repeats. APC2 promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. It may function in Wnt signaling.

Partner Proteins

CTNNB1; NFX1; UBC; CDC27; ANAPC4; ANAPC10; CDC16; CDC23; ANAPC11; ANAPC7; ANAPC5; CDC26; CDH1; ANAPC1; MAPRE3; MAPRE1; Axin1; AXIN2; ACTA1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LAVARIDQLVEDISALHTSSDDSFSLSSGDPGQEAPREGRAQSCSPCRGP

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

244kDa

Protein Length

2303

NCBI Gene Symbol

APC2

Host or Source

Rabbit

Protein Name

Anaphase-promoting complex subunit 2

Gene Name URL

APC2

Nucleotide Accession Number

NM_005883

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