RB1CC1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

RB1-inducible coiled-coil 1

Gene Aliases

CC1, ATG17, FIP200, PPP1R131

Gene ID

9821

Swiss Prot

Q8TDY2

Accession Number

NP_001077086

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human RB1CC1

Target

RB1CC1 is implicated in the regulation of RB1 expression. It functions as a DNA-binding transcription factor. RB1CC1 is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. The expression of RB1CC1 is, thus, a prerequisite for myogenic differentiation. RB1CC1 is frequently mutated in breast cancer and shows characteristics of a classical tumor suppressor gene.

Partner Proteins

ATG16L1; SESN2; ATG5; UBC; EXOC1; DYRK2; PINK1; CALCOCO2; RFWD2; CTNNB1; GABARAPL1; GABARAP; VHL; RNF111; SMARCB1; SKIL; SKI; TBKBP1; TP53; ATG13; ULK2; SAFB2; ULK1; SAFB; RPA2; RPA1; PRKAB2; PRKAA2; HSBP1; MAP1LC3C; SMCR8; ATG101; YLPM1; TBK1; RBMX; PTK2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

183kDa

Protein Length

1591

NCBI Gene Symbol

RB1CC1

Host or Source

Rabbit

Protein Name

RB1-inducible coiled-coil protein 1

Gene Name URL

RB1CC1

Nucleotide Accession Number

NM_001083617

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