LN28B Antibody - C-terminal region (ARP50332_P050)

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Product Specifications

CAS Number

9007-83-4

Gene Name

Lin-28 homolog B

Gene Aliases

CSDD2

Gene ID

389421

Swiss Prot

Q6ZN17

Accession Number

NP_001004317

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human LN28B

Target

The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation.

Partner Proteins

LARP4; ZCCHC3; NIFK; NHP2; NOP10; PHAX; LARP7; TRUB2; PTCD1; RBM34; NCBP2; RALY; KRR1; EIF4A3; SNRPG; SNRPF; SNRPB2; SNRPA; PURB; PURA; NCBP1; FBL; ELAVL2; TRIM71; UBC; COPS5; USP36

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GCTSPPFPQEARAEISERSGRSPQEASSTKSSIAPEEQSKKGPSVQKRKK

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol