WNT3 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Wingless-type MMTV integration site family, member 3

Gene Aliases

INT4, TETAMS

Gene ID

7473

Swiss Prot

P56703

Accession Number

NP_110380

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human WNT3

Target

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.

Partner Proteins

FZD1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SHHKGPPGEGWKWGGCSEDADFGVLVSREFADARENRPDARSAMNKHNNE

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

37kDa

Protein Length

355

NCBI Gene Symbol

WNT3

Host or Source

Rabbit

Protein Name

Proto-oncogene Wnt-3

Gene Name URL

WNT3

Nucleotide Accession Number

NM_030753

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

PVTB01076-1 2 µg

pDONR223-FYB Plasmid

Ask

View Details

7060125 12/Bag

Bottle, Narrow Mouth, Round, HDPE, 125mL

Ask

View Details

MR203321L3V 200 µL

Enoph1 (NM_026421) Mouse Tagged ORF Clone Lentiviral Particle

Ask

View Details

MF-0072666 100 µg

Anti-DDR1 Antibody-Biotin (1U273)

Ask

View Details

MBS6385254-01 0.1 mL

MEF2D (Myocyte-specific Enhancer Factor 2D, DKFZp686I1536) (MaxLight 550)

Ask

View Details

MBS6385254-02 5x 0.1 mL

MEF2D (Myocyte-specific Enhancer Factor 2D, DKFZp686I1536) (MaxLight 550)

Ask

View Details