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CLC7A Antibody - N-terminal region (ARP49740_P050)

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Product Specifications

Gene Name

C-type lectin domain containing 7A

Gene Aliases

BGR, CD369, CANDF4, SCARE2, DECTIN1, CLECSF12

Gene ID

64581

Swiss Prot

Q9BXN2

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human CLC7A

Target

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Partner Proteins

BNIP3; SYNE4; SMIM3; JAGN1; TMEM79; ADAM33; CLEC7A; FAM3A; TMPRSS4; IL1RL1; OCLN; NINJ2; KTN1; CALM3; PTTG1IP; BNIP3L; RANBP9; AIP; HSPD1; SOCS1; TLR2; UBC

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GYTQLHFDSQSNTRIAVVSEKGSCAASPPWRLIAVILGILCLVILVIAVV

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

27kDa

Protein Length

247

NCBI Gene Symbol

CLEC7A

Host or Source

Rabbit

Protein Name

C-type lectin domain family 7 member A

Gene Name URL

CLEC7A

CAS Number

9007-83-4

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