POLR1B Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Polymerase (RNA) I polypeptide B, 128kDa

Gene Aliases

A135, RPA2, TCS4, RPA135, Rpo1-2

Gene ID

84172

Swiss Prot

Q9H9Y6

Accession Number

NP_061887

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human POLR1B

Target

Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]) .

Partner Proteins

UBC; RPA3; RPA2; RPA1; RRN3; HDAC6; GIT2; MED20; NMI; LDB1; ZNF207; RPL37; CCND1; AKT2; ACTA1; ERBB2; ACTB; TSR1; POLR1D; POLR1A; CD3EAP; NOP56; POLR1C; DHX8; CAND1; ARRB2; LZTR1; TAF1D; USP11; POLR1E; EIF3L; NFKBIB; POLR1B; ESR1; RIBIN

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SDKFQVRTTGARDRVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHD

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 93%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

128kDa

Protein Length

1135

NCBI Gene Symbol

POLR1B

Host or Source

Rabbit

Protein Name

DNA-directed RNA polymerase I subunit RPA2

Gene Name URL

POLR1B

Nucleotide Accession Number

NM_019014

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