METTL1 antibody - middle region (ARP48665_T100)

Product Specifications

CAS Number

9007-83-4

Gene Name

Methyltransferase like 1

Gene Aliases

TRM8, TRMT8, C12orf1, YDL201w

Gene ID

4234

Swiss Prot

Q9UBP6

Accession Number

NP_005362

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human METTL1

Target

METTL1 contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation.This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X.

Partner Proteins

WDR4; AKT1; TRM8; PDLIM5; ARPC2; ACTR2; ACTR3; ARPC1B; ARPC4; ARPC5; TOM1L1; KIAA0101; UBE3A; TPD52L2; PRDX2; PRKDC; PRDX1; NUCB1; GTF2I; DR1; AARS; TP53RK; NIF3L1; CTPS2; NPLOC4; DNAAF5; IPO11; TPRKB; CACYBP; KIAA1279; METTL18; UBC; RPS6KA1; RPS6KA3

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

KGQLTKMFFLFPDPHFKRTKHKWRIISPTLLAEYAYVLRVGGLVYTITDV

Applications

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 87%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

34kDa

Protein Length

301

NCBI Gene Symbol

METTL1

Host or Source

Rabbit

Protein Name

TRNA (guanine-N (7) -) -methyltransferase

Gene Name URL

METTL1

Nucleotide Accession Number

NM_005371

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