PYGB Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Phosphorylase, glycogen; brain

Gene Aliases

GPBB

Gene ID

5834

Swiss Prot

P11216

Accession Number

NP_002853

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PYGB

Target

PYGB is a glycogen phosphorylase found predominantly in the brain. It forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBC; SIAH1; PYGL; PYGB; SUMO2; SUMO3; WDR61; RIC8A; OGFOD1; UBA6; UBR7; LIMD1; XPNPEP1; PLCG1; FH; NPM1; CPNE1; PSMB2; CAND1; SIRT7; MLH1; ACTN1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDT

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 85%; Dog: 92%; Guinea Pig: 86%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 92%; Sheep: 85%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

97kDa

Protein Length

843

NCBI Gene Symbol

PYGB

Host or Source

Rabbit

Protein Name

Glycogen phosphorylase, brain form

Gene Name URL

PYGB

Nucleotide Accession Number

NM_002862

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MR227441L4V 200 µL

Gemin2 (NM_025656) Mouse Tagged ORF Clone Lentiviral Particle

Ask

View Details

463791-01 25 mg

(R) -3-Amino-3- (6-methoxy-3-pyridyl) -propionic acid

Ask

View Details

463791-02 50 mg

(R) -3-Amino-3- (6-methoxy-3-pyridyl) -propionic acid

Ask

View Details

KLW0166 1x 96 Well

GENLISA™ Monkey for Enolase Neuron Specific (NSE) ELISA

Ask

View Details

QH58749S 200 Tests

Human NT5C1B qPCR Primer Pair

Ask

View Details

P519928 100 µg

Spike Protein (C-His, SARS-CoV-2)

Ask

View Details