PHB2 Antibody - C-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Prohibitin 2

Gene Aliases

BAP, REA, p22, hBAP, Bap37, BCAP37, PNAS-141

Gene ID

11331

Swiss Prot

Q99623

Accession Number

NP_009204

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human PHB2

Target

PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity) . It functions as an estrogen receptor (ER) -selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.

Partner Proteins

HUWE1; IGF1R; HDAC1; ESR1; KIAA1244; NCOR1; SUMO2; STAU1; UBC; MDM2; ASB14; ASB17; SUZ12; EED; RNF2; UPF2; ADRB2; CDK2; env; VCAM1; TEAD3; ITGA4; ILF3; FN1; ATF2; C1QBP; AFP; UBL4A; EPAS1; FMNL1; PAXIP1; MDC1; MYOD1; MEF2A; FHL2; ECT2; BRCA1; AKT1; Htt; U

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

KLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

33kDa

Protein Length

299

NCBI Gene Symbol

PHB2

Host or Source

Rabbit

Protein Name

Prohibitin-2

Gene Name URL

PHB2

Nucleotide Accession Number

NM_007273

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