LDHB Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Lactate dehydrogenase B

Gene Aliases

LDH-B, LDH-H, LDHBD, TRG-5, HEL-S-281

Gene ID

3945

Swiss Prot

P07195

Accession Number

NP_002291

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human LDHB

Target

This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.

Partner Proteins

UBC; PEX5; LDHB; LDHA; FUS; HUWE1; SUMO2; SUMO3; STAU1; SUZ12; RNF2; GINS4; TXNDC5; FTO; UBFD1; CNDP2; YWHAQ; BZW1; NPEPPS; SLC9A3R1; YWHAZ; YWHAG; ALDH7A1; YWHAB; UBE2V1; TGM2; RPS6KA1; PGD; PFAS; PAK2; PAFAH1B3; PAFAH1B2; HNRNPAB; HNRNPA2B1; HMGB2; GNAI

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MYGIENEVFLSLPCILNARGLTSVINQKLKDDEVAQLKKSADTLWDIQKD

Applications

IHC, WB, IP

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%; Zebrafish: 91%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

37kDa

Protein Length

334

NCBI Gene Symbol

LDHB

Host or Source

Rabbit

Protein Name

L-lactate dehydrogenase B chain

Gene Name URL

LDHB

Nucleotide Accession Number

NM_002300

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