LDHB Antibody - C-terminal region (ARP48210_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Lactate dehydrogenase B

Gene Aliases

LDH-B, LDH-H, LDHBD, TRG-5, HEL-S-281

Gene ID

3945

Swiss Prot

P07195

Accession Number

NP_002291

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human LDHB

Target

This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.

Partner Proteins

UBC; PEX5; LDHB; LDHA; FUS; HUWE1; SUMO2; SUMO3; STAU1; SUZ12; RNF2; GINS4; TXNDC5; FTO; UBFD1; CNDP2; YWHAQ; BZW1; NPEPPS; SLC9A3R1; YWHAZ; YWHAG; ALDH7A1; YWHAB; UBE2V1; TGM2; RPS6KA1; PGD; PFAS; PAK2; PAFAH1B3; PAFAH1B2; HNRNPAB; HNRNPA2B1; HMGB2; GNAI

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MYGIENEVFLSLPCILNARGLTSVINQKLKDDEVAQLKKSADTLWDIQKD

Applications

IHC, WB, IP

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol