What is the catalog number for CRYAB Antibody - C-terminal region?

The catalog number for CRYAB Antibody - C-terminal region is ARP48196_T100-25UL.

What sizes are available for CRYAB Antibody - C-terminal region?

CRYAB Antibody - C-terminal region is available in the following size(s): 25 µL.

Is CRYAB Antibody - C-terminal region in stock?

CRYAB Antibody - C-terminal region is currently made to order / not held in immediate stock. Contact us for lead time.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

CRYAB Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Crystallin, alpha B

Gene Aliases

MFM2, CRYA2, CTPP2, HSPB5, CMD1II, CTRCT16, HEL-S-101

Gene ID

1410

Swiss Prot

P02511

Accession Number

EAW67166

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CRYAB

Target

Alpha crystallins are composed of: alpha-A and alpha-B, for acidic and basic, respectively. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy.

Partner Proteins

CRYAB; CRYAA; KRTAP19-5; KRTAP8-1; TRAPPC6A; MRPL11; TNPO2; ACOT7; HSPB1; CASP7; CASP3; CASP2; PIDD1; DDX20; CRADD; B2M; APOC2; XIAP; CASP12; SOD1; HSPB2; HBA1; CASP9; CASP8; CASP6; ASB5; SMAD4; TRIM33; UBC; CCL22; CTNNB1; CRYGD; CDH1; SNCA; GFAP; FGF2; F

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

KYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVT

Applications

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol