VATE1 Antibody - N-terminal region (ARP48189_P050)

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Product Specifications

CAS Number

9007-83-4

Gene Name

ATPase H+ transporting V1 subunit E1

Gene Aliases

P31, Vma4, ATP6E, ARCL2C, ATP6E2, ATP6V1E

Gene ID

529

Swiss Prot

P36543

Accession Number

NP_001687

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human VATE1

Target

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome.

Partner Proteins

UBC; SAMHD1; ATP6V1G1; ZNF827; SFXN1; TMEM43; SLC30A5; SUGP1; ZFR; ATP6V1H; ATP6V1D; TCIRG1; ALYREF; PPIF; SCAMP3; SCO2; ATP6V1F; VAPA; LAMTOR3; PICALM; YES1; XPNPEP1; TYMS; THY1; SSBP1; SRSF3; S100A10; YBX1; CD55; ABCC2; ATP6V0A1; ATP6V1C1; ATP6V1B2; ATP

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

IEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEKQIEQQK

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol