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TPI1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Triosephosphate isomerase 1

Gene Aliases

TIM, TPI, TPID, HEL-S-49

Gene ID

7167

Swiss Prot

P60174

Accession Number

NP_000356

Reactivity

Human, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TPI1

Target

TPI1 belongs to the triosephosphate isomerase family. Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) . TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection.

Partner Proteins

MDM2; UBC; RNF2; EZH2; SUZ12; TARDBP; YWHAQ; SP1; UBD; HCVgp1; IQCB1; ATF2; LIG4; SSU72; SEC23IP; PDIA6; PRDX6; VCL; UBA52; TKT; PGK1; MPST; GPI; GAPDH; ENO1; APP; CUL1; CDK2; TERF1; POT1; PSMA3; MAPK6; PCNA; HDAC5; UCHL5; EGFR; LIPT1; SETDB1; DDX24; CFL1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MAPSRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPADTEVVCAPPTAYID

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 79%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Rabbit: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

27kDa

Protein Length

249

NCBI Gene Symbol

TPI1

Host or Source

Rabbit

Protein Name

Triosephosphate isomerase

Gene Name URL

TPI1

Nucleotide Accession Number

NM_000365

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