EIF4A1 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Eukaryotic translation initiation factor 4A1

Gene Aliases

DDX2A, EIF4A, EIF-4A, eIF4A-I, eIF-4A-I

Gene ID

1973

Swiss Prot

P60842

Accession Number

NP_001407

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human EIF4A1

Target

EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Partner Proteins

HUWE1; UBC; FUS; SUMO2; SUMO3; STAU1; MDM2; SH3RF2; TRAP1; FBXO6; ADRB2; CD81; NPM1; VCAM1; ITGA4; FN1; ESR1; LIG4; RPLP0P6; TMEM43; NDUFB11; ZBTB43; GPRC5A; EIF4G3; EIF4H; VDAC3; UQCRFS1; SDHA; RPS26; RPL19; RPL8; RPSA; ILF2; HSP90AB1; HSPA5; EIF4G2; EIF

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

TMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLC

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%; Yeast: 92%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

Protein Length

406

NCBI Gene Symbol

EIF4A1

Host or Source

Rabbit

Protein Name

Eukaryotic initiation factor 4A-I

Gene Name URL

EIF4A1

Nucleotide Accession Number

NM_001416

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