AKT1S1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

AKT1 substrate 1 (proline-rich)

Gene Aliases

Lobe, PRAS40

Gene ID

84335

Swiss Prot

Q96B36

Accession Number

NP_115751

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human AKT1S1

Target

AKT1S1 may play an important role in phosphatidylinositol 3-kinase (PI3K) -AKT1 survival signaling. It is the substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. Its role in survival signaling pathways may be modulated by oxidative stress. AKT1S1 may also play a role in nerve growth factor-mediated neuroprotection.AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]) .[supplied by OMIM].

Partner Proteins

MTOR; RPTOR; SGK1; RICTOR; MAPKAP1; MLST8; FAM114A1; YWHAQ; YWHAB; SQSTM1; RPS6KA5; TCEA2; YWHAG; EIF6; AKT2; AKT1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

KSLPVSVPVWGFKEKRTEARSSDEENGPPSSPDLDRIAASMRALVLREAE

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

27kDa

Protein Length

256

NCBI Gene Symbol

AKT1S1

Host or Source

Rabbit

Protein Name

Proline-rich AKT1 substrate 1

Gene Name URL

AKT1S1

Nucleotide Accession Number

NM_032375

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP2-33102JF549 0.1 mL

Mouse Monoclonal NF-H Antibody (NF421) [Janelia Fluor 549]

Ask

View Details

SC328307 10 µg

ASTN2 (NM_001184735) Human Untagged Clone

Ask

View Details

QP5993-ec-10ug 10ug

Recombinant Human HER2/ ErbB2 Protein, His, E.coli-10ug

Ask

View Details

FAB4398X 0.1 mL

Rat Monoclonal CD39/ENTPD1 Antibody (495826) [Alexa Fluor 532]

Ask

View Details