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NDE1 Antibody - middle region (ARP47931_P050)

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Product Specifications

CAS Number

9007-83-4

Gene Name

NudE nuclear distribution E homolog 1 (A. nidulans)

Gene Aliases

NDE, LIS4, MHAC, NUDE, NUDE1, HOM-TES-87

Gene ID

54820

Swiss Prot

Q9NXR1

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human NDE1

Target

This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe mental retardation. Alternative splicing results in multiple transcript variants.

Partner Proteins

FAM9B; LZTS2; USHBP1; NDEL1; ZNF398; NDE1; WAC; UBQLN1; MED4; DISC1; TFIP11; CEP250; NDC80; ARNT2; BZRAP1; MKRN3; TTC1; TRIM27; REL; HOXA2; GOLGA2; AR; YWHAQ; PAFAH1B1; ZNF365; YWHAG; TUBG1; MAPK1; CDK1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQK

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

38kDa

Protein Length

346

NCBI Gene Symbol

NDE1

Host or Source

Rabbit

Protein Name

Nuclear distribution protein nudE homolog 1

Gene Name URL

NDE1

Frequently Asked Questions

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