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NECTIN2 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Nectin cell adhesion molecule 2

Gene Aliases

HVEB, PRR2, CD112, PVRL2, PVRR2

Gene ID

5819

Swiss Prot

Q0MSE5

Accession Number

NP_002847

Reactivity

Human, Mouse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PVRL2

Target

This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Partner Proteins

KRTAP10-3; KRTAP10-5; KRTAP10-1; KRTAP10-7; NOTCH2NL; SIAH1; MDFI; KRTAP5-9; TIGIT; PVRL4; TNFRSF12A; PVRL3; PVRL2; LYRM4; DUS2; USP53; UBC; MAPK6; ATP5J2; PICK1; CD226; MLLT4

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MEPDGKDEEEEEEEEKAEKGLMLPPPPALEDDMESQLDGSLISRRAVYV

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%; Mouse: 93%; Pig: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

48kDa

Protein Length

479

NCBI Gene Symbol

NECTIN2

Host or Source

Rabbit

Protein Name

Nectin-2

Gene Name URL

NECTIN2

Nucleotide Accession Number

NM_002856

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