RNF213 Antibody - N-terminal region (ARP47667_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Ring finger protein 213

Gene Aliases

ALO17, MYMY2, MYSTR, NET57, C17orf27, KIAA1618

Gene ID

57674

Swiss Prot

Q63HN8-5

Accession Number

NP_066005

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human RNF213

Target

This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t (2;17) (p23; q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t (8;17) (q24; q25) translocation has been identified with the MYC gene on chromosome 8.

Partner Proteins

KRT40; UBXN11; TRIP6; TRIM27; REL; GOLGA2; TRIM23; UBC; RNF213; EGFR; PLAC9; CBX2; vpu; CBX6; CBX4; tat

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ETGNNSVQTVFQGTLAATKRWLREVFTKNMLTSSGASFTYVKEIEVWRRL

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol