DDOST Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase

Gene Aliases

OST, WBP1, AGER1, CDG1R, GATD6, OST48, OKSWcl45

Gene ID

1650

Swiss Prot

Q5VWA5

Accession Number

NP_005207

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DDOST

Target

DDOST is a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. DDOST is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.

Partner Proteins

HUWE1; VAPB; UBC; FAF1; STAU1; ASB11; TRIM13; SUZ12; EED; CLN3; NXT1; SRSF11; FN1; ATF2; STT3B; MAGT1; ZMPSTE24; VDAC2; SSR4; SSR3; SLC25A3; ILF2; KRTCAP2; FBXO6; UBD; AMFR; AUP1; TMEM173; UNC93B1; MAPK6; HDAC5; AGO3; BRCC3; GSTK1; TMBIM4; PGRMC1; SAP18

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SPSVEDFGGNINVETISAFIDGGGSVLVAASSDIGDPLRELGSECGIEFD

Applications

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol