CDT1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Chromatin licensing and DNA replication factor 1

Gene Aliases

DUP, RIS2

Gene ID

81620

Swiss Prot

Q9H211

Accession Number

NP_112190

Reactivity

Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CDT1

Target

CDT1 cooperates with CDC6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the pre-replication complex necessary to initiate DNA replication. It binds DNA in a sequence-, strand-, and conformation-independent manner and is a potential oncogene.

Partner Proteins

FBXO31; SKP1; RBX1; CUL1; DTL; PCNA; HECW2; CDK2; CDC6; CDC5L; ORC2; ORC1; GMNN; DGCR8; UBC; SKP2; CDK1; CCNB1; CCNA2; FOXO3; DDB1; COPS5; CUL4A; CUL4B; SMARCA5; MCM6; MAPK8; MAPK1; HDAC11; KAT7; CCNA1; DDB2; CDK4; CCNE1; TP63; TP73; EP300; KAT2B; CDT1; U

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PATPPATPPAASPSALKGVSQDLLERIRAKEAQKQLAQMTRCPEQEQRLQ

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 77%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%; Yeast: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

60kDa

Protein Length

546

NCBI Gene Symbol

CDT1

Host or Source

Rabbit

Protein Name

DNA replication factor Cdt1

Gene Name URL

CDT1

Nucleotide Accession Number

NM_030928

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