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NCAPD2 Antibody - C-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Non-SMC condensin I complex, subunit D2

Gene Aliases

CNAP1, CAP-D2, MCPH21, hCAP-D2

Gene ID

9918

Swiss Prot

Q15021

Accession Number

NP_055680

Reactivity

Human, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human NCAPD2

Target

NCAPD2 is the regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. NCAPD2 may target the condensin complex to DNA via its C-terminal domain.

Partner Proteins

UBC; NCAPG; CCAR2; NCAPH; SMC2; SMC4; TXNL1; RABEP1; PABPC4; RPS5; FLNC; SOX2; CSNK2A1; PAXIP1; PNPT1; NUP153; MEA1; HSPD1; C1QBP; SIRT7; CDK1; RAD21; SIRT3; tat; PARP1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

KAIIDEFEQKLRACHTRGLDGIKELEIGQAGSQRAPSAKKPSTGSRYQPL

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Dog: 79%; Horse: 93%; Human: 100%; Pig: 92%; Rabbit: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

157kDa

Protein Length

1401

NCBI Gene Symbol

NCAPD2

Host or Source

Rabbit

Protein Name

Condensin complex subunit 1

Gene Name URL

NCAPD2

Nucleotide Accession Number

NM_014865

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