MRPL10 Antibody - N-terminal region (ARP46168_P050)
Product Specifications
CAS Number
9007-83-4
Gene Name
Mitogen-activated protein kinase kinase kinase kinase 1
Gene Aliases
L10MT, MRPL8, RPML8, MRP-L8, MRP-L10
Gene ID
124995
Swiss Prot
Q7Z7H8-2
Accession Number
NP_683685
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human MRPL10
Target
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 5q.
Partner Proteins
FAM9B; KLHL12; PNMA1; TCF4; REL; UBC; NPM1; MRPL1; MRPL11; MRPL41; MRPL15; MRPL13; MRPL3; MRPL12; MRPL23; SLC25A3; ILF3; ICT1; HNRNPU; ABCC2; BCS1L; APP; ABCB7; MRPL10; USP22
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
HLPGSSDSPASASQVAGITGRLPTLQTVRYGSKAVTRHRRVMHFQRQKLM
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
29kDa
Protein Length
271
NCBI Gene Symbol
MRPL10
Host or Source
Rabbit
Protein Name
39S ribosomal protein L10, mitochondrial
Gene Name URL
MRPL10
Nucleotide Accession Number
NM_148887
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