SMC4 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Structural maintenance of chromosomes 4

Gene Aliases

CAPC, CAP-C, SMC-4, SMC4L1

Gene ID

10051

Swiss Prot

Q9NTJ3

Accession Number

NP_001002800

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SMC4

Target

SMC4 is the central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Partner Proteins

UBC; SUMO2; LGR4; RPA3; RPA2; RPA1; RNF2; NCAPH; SMC2; SSSCA1; NCAPD2; TBC1D4; PLEC; AP3S1; CDK9; NCAPG; CCAR2; RABL6; TOPBP1; FBXO6; UBD; HDAC11; MYC; Nfe2l2; NEDD8; CDK2; SIRT7; NCAPH2; NCAPD3; RAD21; TRAF3IP1; SUMO1; HDAC1; tat; DNMT3B

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRK

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol