DFNA5 antibody - C-terminal region (ARP46106_T100)
Product Specifications
CAS Number
9007-83-4
Gene Name
Gasdermin E
Gene Aliases
DFNA5, ICERE-1
Gene ID
1687
Swiss Prot
A4FVA8
Accession Number
AAI25067
Reactivity
Human, Rat, Cow, Dog, Guinea Pig
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human DFNA5
Target
Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.
Partner Proteins
UBC; EGFR; PTN
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
AALLGTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQR
Applications
IHC, WB
Purification
Protein A purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1.0 mg/ml
Homology
Cow: 85%; Dog: 77%; Guinea Pig: 83%; Human: 100%; Rat: 85%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
47kDa
Protein Length
437
NCBI Gene Symbol
GSDME
Host or Source
Rabbit
Protein Name
Gasdermin-E
Gene Name URL
GSDME
Nucleotide Accession Number
NM_001127453
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