HSPA4 antibody - N-terminal region (ARP46073_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Heat shock 70kDa protein 4

Gene Aliases

RY, APG-2, HSPH2, hsp70, hsp70RY, HEL-S-5a, HS24/P52

Gene ID

3308

Swiss Prot

P34932

Accession Number

NP_002145

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human HSPA4

Target

HSPA4 (Hsp70) belongs to the heat shock protein 70 family. It was isolated as a putative Rictor interacting protein and interaction with membranes acts as a platform for its release into the extracellular environment during its recovery from stress. Hsp70 gene expression in Rheumatoid Arthitis-affected synovial tissue is followed by Hsp70 cell surface expression on fibroblast-like synovial cells growing from RA synovial tissue. Serum Hsp70 levels were increased in Systemic sclerosis patients, and associated with pulmonary fibrosis, skin sclerosis, renal vascular damage, oxidative stress, and inflammation.

Partner Proteins

TP53; CDC25C; CDK1; AGTRAP; ERLIN2; HUWE1; Slc12a3; APPBP2; PSMD10; UBC; SUMO2; SUMO3; SIK2; MAP3K11; VHL; UIMC1; PRKCG; PRKCD; STUB1; HIF1A; ENDOG; HSPA8; TRIM5; USP19; PA2G4; WWOX; NDRG1; GZMA; GART; CRMP1; CDKN2A; CARS; PPM1G; PPAT; KARS; FAM114A1; HSP

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PACISFGPKNRSIGAAAKSQVISNAKNTVQGFKRFHGRAFSDPFVEAEKS

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol