SMC2 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Structural maintenance of chromosomes 2

Gene Aliases

CAPE, CAP-E, SMC-2, SMC2L1

Gene ID

10592

Swiss Prot

O95347

Accession Number

AAH03396

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SMC2

Target

SMC2 is the central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Partner Proteins

UBC; RPA3; RPA2; RPA1; NCAPG; CCAR2; NCAPH; SSSCA1; SMC4; NCAPD2; PLEC; CDK9; FBXO6; EGFR; SOX2; GULP1; ABCC5; PAXIP1; SMC1A; UBD; NEDD8; SUMO2; NCAPG2; NCAPH2; NCAPD3; RAD21; LIG4; HIST2H3C; DISC1; TRAF3IP1; HIST2H2BE; HIST2H2AC; H2AFZ; MYC; tat; DNMT3B

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ISNLSQVRASNLQDLVYKNGQAGITKASVSITFDNSDKKQSPLGFEVHDE

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol