SMC2 antibody - N-terminal region (ARP46043_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Structural maintenance of chromosomes 2

Gene Aliases

CAPE, CAP-E, SMC-2, SMC2L1

Gene ID

10592

Swiss Prot

O95347

Accession Number

AAH03396

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SMC2

Target

SMC2 is the central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Partner Proteins

UBC; RPA3; RPA2; RPA1; NCAPG; CCAR2; NCAPH; SSSCA1; SMC4; NCAPD2; PLEC; CDK9; FBXO6; EGFR; SOX2; GULP1; ABCC5; PAXIP1; SMC1A; UBD; NEDD8; SUMO2; NCAPG2; NCAPH2; NCAPD3; RAD21; LIG4; HIST2H3C; DISC1; TRAF3IP1; HIST2H2BE; HIST2H2AC; H2AFZ; MYC; tat; DNMT3B

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ISNLSQVRASNLQDLVYKNGQAGITKASVSITFDNSDKKQSPLGFEVHDE

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 86%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

32kDa

Protein Length

289

NCBI Gene Symbol

SMC2

Host or Source

Rabbit

Protein Name

Structural maintenance of chromosomes protein 2

Gene Name URL

SMC2

Nucleotide Accession Number

NM_001042550

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