What is the catalog number for COL18A1 Antibody - Middle region (ARP45877_P050)?

The catalog number for COL18A1 Antibody - Middle region (ARP45877_P050) is ARP45877_P050.

What sizes are available for COL18A1 Antibody - Middle region (ARP45877_P050)?

COL18A1 Antibody - Middle region (ARP45877_P050) is available in the following size(s): 100 µL.

Is COL18A1 Antibody - Middle region (ARP45877_P050) in stock?

COL18A1 Antibody - Middle region (ARP45877_P050) is currently made to order / not held in immediate stock. Contact us for lead time.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

COL18A1 Antibody - Middle region (ARP45877_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Collagen, type XVIII, alpha 1

Gene Aliases

KS, KNO, GLCC, KNO1

Gene ID

80781

Swiss Prot

P39060-2

Reactivity

Human, Cow, Horse, Pig, Rabbit

Immunogen

The immunogen for Anti-COL18A1 antibody is: synthetic peptide directed towards the Middle region of Human COIA1

Target

This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants.

Partner Proteins

FUS; TUBG1; FBXO6; HNRNPD; TECPR1; GPC1; GPC4; KDR; FBLN2; ITGA5; MMP2; CTSL

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

VQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADD

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol