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KNG1 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Kininogen 1

Gene Aliases

BK, BDK, KNG, HMWK

Gene ID

3827

Swiss Prot

P01042

Accession Number

NP_001095886

Reactivity

Human, Mouse, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human KNG1

Target

Kininogens are inhibitors of thiol proteases. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII and inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. The active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects such as influence in smooth muscle contraction, induction of hypotension, natriuresis and diuresis, etc.

Partner Proteins

Ance; ECE1; COPS6; RXFP4; CPN1; F11; HABP2; CTSK; PREP; MEP1A; ITGB2; GP1BA; KLKB1; KNG1; VTN; THBS1; F2; PLAUR; PLG; KLK1; KRT1; FTL; ELANE; CD93; CTSL; CTSS; CTSG; CAPN2; CAPN1; AGT; APP

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

YPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFK

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Horse: 85%; Human: 100%; Mouse: 77%; Pig: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

72kDa

Protein Length

644

NCBI Gene Symbol

KNG1

Host or Source

Rabbit

Protein Name

Kininogen-1

Gene Name URL

KNG1

Nucleotide Accession Number

NM_001102416

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