NR1I3 antibody - N-terminal region (ARP45623_T100)

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Product Specifications

CAS Number

9007-83-4

Gene Name

Nuclear receptor subfamily 1, group I, member 3

Gene Aliases

CAR, CAR1, MB67

Gene ID

9970

Swiss Prot

Q5VTW5

Accession Number

NP_005113

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NR1I3

Target

NR1I3 mediates the induction of transcription of cytochrome P450 (CYP) genes by phenobarbital (PB) and PB-type inducers. NR1I3 activation induces hepatic expression of detoxification enzymes and transporters and increases liver size. NR1I3 can also regulate both liver homeostasis and tumorigenesis in response to xenobiotic stresses.

Partner Proteins

HSP90AA1; RXRA; CHD9; SNX13; SNRPD3; IGH; PSMC5; PSMC4; EIF3I; SRC; MAP4; FTH1; HNF4A; NR0B2; PPARGC1A; MED1; NCOA1; POU1F1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA

Applications

IHC, WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol