NR4A1 antibody - middle region (ARP45604_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Nuclear receptor subfamily 4, group A, member 1

Gene Aliases

HMR, N10, TR3, NP10, GFRP1, NAK-1, NGFIB, NUR77

Gene ID

3164

Swiss Prot

P22736

Accession Number

NP_002126

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human NR4A1

Target

NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Partner Proteins

KRTAP10-5; KRTAP10-1; LONRF1; PGBD1; BCL2L10; CDKN2D; BCL2A1; BCL2; TUBB4A; VASP; ANKIB1; CUTA; NFKB1; SMAD3; LSS; HADHA; GLUD1; GK; CPT1A; SERPING1; ABCC6; ABCC13; SOCS4; ABCG8; DIABLO; HCVgp1; ABCA5; CHEK2; SUGT1; PRDX4; PRDX6; CHD1L; ABCB11; ARHGEF5; U

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

FQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAHL

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 85%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

64 kDa

Protein Length

598

NCBI Gene Symbol

NR4A1

Host or Source

Rabbit

Protein Name

Nuclear receptor subfamily 4 group A member 1

Gene Name URL

NR4A1

Nucleotide Accession Number

NM_002135

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