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OS9 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Osteosarcoma amplified 9, endoplasmic reticulum lectin

Gene Aliases

OS-9, ERLEC2

Gene ID

10956

Swiss Prot

Q13438

Accession Number

NP_006803

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human OS9

Target

This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Partner Proteins

SYVN1; SEL1L; UBC; DCSTAMP; SERPINI1; FBXO6; EGFR; DERL2; CLN5; SNRPD2; SMAD2; FOXM1; ACVR1B; ZNF512B; env; CREB3; RBX1; UBE2J1; CERCAM; NUP210; OS9; HYOU1; VCP; HSP90B1; PPIB; PLOD2; HSPA5; SERPINH1; BSG; FOXRED2; COLGALT1; UGGT2; DNAJB11; ERLEC1; HIF1A

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPGGEGTGDLDEFDF

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 86%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

73kDa

Protein Length

667

NCBI Gene Symbol

OS9

Host or Source

Rabbit

Protein Name

Protein OS-9

Gene Name URL

OS9

Nucleotide Accession Number

NM_006812

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