ITM2C Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Integral membrane protein 2C

Gene Aliases

E25, BRI3, E25C, ITM3, BRICD2C

Gene ID

81618

Swiss Prot

Q9NQX7

Accession Number

NP_112188

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Target

ITM2C is a negative regulator of beta amyloid peptide production. ITM2C may inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor.ITM2C may play a role in TNF-induced cell death and neuronal differentiation.

Partner Proteins

UBC; Dlg4; RYK; BACE1; RNF7; STT3A; MTNR1B; FURIN

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EDSLSSQVRTQMELEEDVKIYLDENYERINVPVPQFGGGDPADIIHDFQR

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 100%; Zebrafish: 91%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

30kDa

Protein Length

267

NCBI Gene Symbol

ITM2C

Host or Source

Rabbit

Protein Name

Integral membrane protein 2C

Gene Name URL

ITM2C

Nucleotide Accession Number

NM_030926

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

20477022 500 ng

FGD2 Protein Vector (Human) (pPM-C-HA)

Ask

View Details

MBS8306385-01 0.03 mL

Anti-Cystatin S Antibody

Ask

View Details

MBS8306385-02 0.05 mL

Anti-Cystatin S Antibody

Ask

View Details

MBS8306385-03 0.1 mL

Anti-Cystatin S Antibody

Ask

View Details

MBS8306385-04 0.2 mL

Anti-Cystatin S Antibody

Ask

View Details

MBS8306385-05 5x 0.2 mL

Anti-Cystatin S Antibody

Ask

View Details