PPIB Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Peptidylprolyl isomerase B (cyclophilin B)

Gene Aliases

B, OI9, CYPB, SCYLP, CYP-S1, HEL-S-39

Gene ID

5479

Swiss Prot

A8K534

Accession Number

NP_000933

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PPIB

Target

PPIB is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression.

Partner Proteins

BANP; UBQLN1; SGTA; PEX19; UBC; MDM2; DDIT3; WWOX; SUZ12; EED; BMI1; rev; RRM1; PPP5C; PFKP; GAPDH; HECW2; FBXO6; UBD; CFTR; ATP12A; VKORC1; OS9; MAGT1; SUGP1; LSM4; TIMM44; SCO2; ZC3H11A; UBL4A; RBMS1; RANGAP1; PCBP2; P4HB; HSPA5; PDIA3; DHX9; ACAA1; MRP

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

FITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADC

Applications

IHC, WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%; Sheep: 86%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

24kDa

Protein Length

216

NCBI Gene Symbol

PPIB

Host or Source

Rabbit

Protein Name

Peptidyl-prolyl cis-trans isomerase B

Gene Name URL

PPIB

Nucleotide Accession Number

NM_000942

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