GHR Antibody - C-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Growth hormone receptor
Gene Aliases
GHBP, GHIP
Gene ID
2690
Swiss Prot
P10912-3
Accession Number
NP_001229391
Reactivity
Human, Dog, Horse, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human GHR
Target
This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein.
Partner Proteins
FBXW11; JAK2; GHR; GH1; BTRC; UBC; SKP1; SOCS2; STUB1; PTPRH; PTPRB; PTPN13; PTPN9; PTPN3; PTPN2; PTPN1; DUSP7; NCOA6; STAT5B; SOCS3; SOCS1; SGTA; CISH; GRB10; STAT5A; AP2A1; SHC1; TYK2; PTPN6; PTPN11; PRLR; PIK3R1; JAK1; IRS1; GH2; GRB2; STAT3; PLCG1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
YSLKVDKEYEVRVRSKQRNSGNYGEFSEVLYVTLPQMSQFTCEEDFYFPW
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Dog: 79%; Horse: 79%; Human: 100%; Pig: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
32kDa
Protein Length
294
NCBI Gene Symbol
GHR
Host or Source
Rabbit
Protein Name
Growth hormone receptor
Gene Name URL
GHR
Nucleotide Accession Number
NM_001242462
Frequently Asked Questions
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