Benastatin B
Benastatin B is an inhibitor for glutathione S-transferase, that inhibits human pi class GST with an IC50 of 1.10 μg/mL. Benastatin B exhibits board-spectrum antibacterial efficacy, inhibits MRSA with MIC 3.1 μg/mL. Benastatin B exhibits anti-inflammatory efficacy through inhibition of IgE mediated β-hexosaminidase release with an IC50 of 79 μg/mL[1][2].
Product Specifications
CAS Number
[138968-86-2]
UNSPSC
12352005
Target
Bacterial; Glutathione S-transferase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/benastatin-b.html
Smiles
O=C(C1=C(C2=C(C=C1CCCCC)CCC3=C2C=C4C(C(C5=C(C4(C)C)C=C(O)C=C5O)=O)=C3O)O)O
Molecular Formula
C30H30O7
Molecular Weight
502.56
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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