SLCO1B1 Antibody - middle region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Solute carrier organic anion transporter family, member 1B1

Gene Aliases

LST1, HBLRR, LST-1, OATP2, OATPC, OATP-C, OATP1B1, SLC21A6, ARP43914_P050

Gene ID

10599

Swiss Prot

Q9Y6L6

Accession Number

NP_006437

Reactivity

Human, Cow, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SLCO1B1

Target

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

IILIYAMKKKYQEKDINASENGSVMDEANLESLNKNKHFVPSAGADSETH

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 86%; Human: 100%; Pig: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

76kDa

Protein Length

691

NCBI Gene Symbol

SLCO1B1

Host or Source

Rabbit

Protein Name

Solute carrier organic anion transporter family member 1B1

Gene Name URL

SLCO1B1

Nucleotide Accession Number

NM_006446

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