SLC9A3R1 Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

SLC9A3 regulator 1

Gene Aliases

EBP50, NHERF, NHERF1, NHERF-1, NPHLOP2

Gene ID

9368

Swiss Prot

O14745

Accession Number

NP_004243

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human NHRF1

Target

This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.

Partner Proteins

ABCC4; UBC; MDM2; CKB; CAPN1; LDHAL6B; FTO; SMEK2; UBFD1; CNDP2; NANS; DAK; YWHAQ; GDA; NPEPPS; RPL23; YWHAZ; YWHAB; TGM2; SMS; RPS6KA3; LDHB; PDIA3; G6PD; ECHS1; CSE1L; CFTR; GNA11; PLCB1; EPHB1; PTEN; BCL10; ZNF468; gag-pol; MDH1; PALM2; PCYOX1; PPME1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

AEKAGLLAGDRLVEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDE

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

39kDa

Protein Length

358

NCBI Gene Symbol

SLC9A3R1

Host or Source

Rabbit

Protein Name

Na (+) /H (+) exchange regulatory cofactor NHE-RF1

Gene Name URL

SLC9A3R1

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