CREBBP Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

CREB binding protein

Gene Aliases

CBP, RSTS, KAT3A, MKHK1, RSTS1

Gene ID

1387

Swiss Prot

Q4LE28

Accession Number

NP_001073315

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CREBBP

Target

CREBBP is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. CREBBP has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain.

Partner Proteins

SUMO1; UBE2I; UBE2D1; TDG; RELA; CREBBP; KLF2; KLF4; WRN; PSME3; COPS2; UBC; BMI1; EID1; ATF4; DYRK1B; DYRK1A; ATF2; CREB1; CDK2; JUN; PPARG; IRF3; HNF4A; KLF1; vIRF-3; AR; vIRF-1; CNTN2; SMAD3; SMAD2; LDLR; STAT1; K8; MTDH; MEIS1; TLR2; EPAS1; MYBL1; LIG

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

TPAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTHPGLLNSNS

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol