PCSK5 Antibody - middle region
Product Specifications
CAS Number
9007-83-4
Gene Name
Proprotein convertase subtilisin/kexin type 5
Gene Aliases
PC5, PC6, PC6A, SPC6
Gene ID
5125
Swiss Prot
Q92824
Accession Number
NP_006191
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human PCSK5
Target
PCSK5 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. PCSK5 mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known.The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
NOTCH2NL; KRTAP10-3; KRTAP10-8; KRTAP10-7; LCE3C; KRTAP4-12; NUFIP2; GLRX3; STK16; MEOX2; KRTAP5-9; env; Hoxa1; ATN1; UBC; CACNA1A; APPBP2; AMH; REN; PTPRM; PMCH; ITGA6
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
CAGAGADGCINCTEGYFMEDGRCVQSCSISYYFDHSSENGYKSCKKCDIS
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
89kDa
Protein Length
913
NCBI Gene Symbol
PCSK5
Host or Source
Rabbit
Protein Name
Proprotein convertase subtilisin/kexin type 5
Gene Name URL
PCSK5
Nucleotide Accession Number
NM_006200
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