TRIM63 Antibody - middle region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Tripartite motif containing 63, E3 ubiquitin protein ligase

Gene Aliases

IRF, SMRZ, MURF1, MURF2, RNF28

Gene ID

84676

Swiss Prot

Q969Q1

Accession Number

NP_115977

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TRIM63

Target

This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle.

Partner Proteins

UBE2D3; UBE2D1; UBC; TRIM63; USP37; ANKIB1; EPN1; ATXN3; EPS15; DCAF6; LMCD1; ANKRD1; NOMO1; GMEB1; NEBL; PIAS3; MRPL19; MYOT; PIAS2; SQSTM1; TCAP; PIAS1; UXT; UQCRC1; TTN; TNNI3; TNNI2; TNNI1; GFM1; TRIM55; MRPL41; MYOZ1; NEB; NDUFA1; MYBPC3; MYBPC1; EIF

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLGKTEQ

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol