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TRIM63 Antibody - C-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Tripartite motif containing 63, E3 ubiquitin protein ligase

Gene Aliases

IRF, SMRZ, MURF1, MURF2, RNF28

Gene ID

84676

Swiss Prot

Q969Q1

Accession Number

NP_115977

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human TRIM63

Target

This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase.

Partner Proteins

UBE2D3; UBE2D1; UBC; TRIM63; USP37; ANKIB1; EPN1; ATXN3; EPS15; DCAF6; LMCD1; ANKRD1; NOMO1; GMEB1; NEBL; PIAS3; MRPL19; MYOT; PIAS2; SQSTM1; TCAP; PIAS1; UXT; UQCRC1; TTN; TNNI3; TNNI2; TNNI1; GFM1; TRIM55; MRPL41; MYOZ1; NEB; NDUFA1; MYBPC3; MYBPC1; EIF

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

TIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQ

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

38kDa

Protein Length

353

NCBI Gene Symbol

TRIM63

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase TRIM63

Gene Name URL

TRIM63

Nucleotide Accession Number

NM_032588

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